Hippocampal spike-timing correlations lead to hexagonal grid fields
Phys Rev Lett 119, 038101 - Published 19 July 2017.
|Type of Publication:||Journal Articles 2001 - 2017|
Space is represented in the mammalian brain by the activity of hippocampal place cells, as well as in their spike-timing correlations. Here, we propose a theory for how this temporal code is transformed to spatial firing rate patterns via spike-timing-dependent synaptic plasticity. The resulting dynamics of synaptic weights resembles well-known pattern formation models in which a lateral inhibition mechanism gives rise to a Turing instability. We identify parameter regimes in which hexagonal firing patterns develop as they have been found in medial entorhinal cortex.